COST ACTION CA18208

Novel tools for test evaluation and disease prevalence estimation

HARMONY

DESCRIPTION OF THE ACTION

Epidemiological studies assessing disease prevalence are critically important to both the identification and control of pathogens in humans and animals (including zoonosis and food borne outbreaks).

However, countries typically collect data in a way that is best suited for their specific needs, and non-standardized sampling strategies and diagnostic methods produce prevalence estimates that cannot be directly compared. Hence, the need for harmonization, which has been often highlighted in reports of relevant EU institutions, like the ECDC and EFSA. Despite the availability of appropriate statistical methods – Bayesian Latent Class Models (BLCMs) – that adjust for the imperfect accuracy of the diagnostic process and produce comparable prevalence estimates, the number of research studies and scientific reports that use them is small compared to the number of instances that use of such methods would have been optimal.

The objective of this proposal is to coordinate and promote the implementation of BLCMs through networking and knowledge transfer between BLCM experts and researchers working in statistics, epidemiology, diagnostics and population health. Specifically, we will (a) increase the visibility and collaboration of BLCM researchers, (b) promote stakeholder engagement, (c) provide training and networking opportunities for ECIs and ITC researchers, (d) create separate training opportunities for policy makers and stakeholders, (e) establish a free online BLCMs repository, (f) set up an International society for BLCMs and (g) organize the first international conference of this society. The strongest asset of this proposal is its strong interdisciplinary nature and broad network of proposers.

Bayesian Latent Class models for diagnostic test evaluation and true prevalence estimation
20 September, 2021 
- 22 September, 2021
Venue: Geopolis Campus, Larissa-Trikala ring-road, Larissa, 41500, Greece
The Action members from Greece are organizing a three-day training school, hosted in Larissa, Greece [20 - 22 September  2021]. Polychronis Kostoulas, Eleftherios Meletis, Konstantinos Pateras and Konstantinos Tsiamis are organizing a three-day training school. Topic "Bayesian Latent Class models for diagnostic test evaluation and true prevalence estimation".
Denmark Training School – Material
Main objective of HARMONY is to promote effective communication, training and understanding Bayesian Latent Class Models (BLCMs). You can access all training material, plus the recording, from the online training school on Diagnostic Test Evaluation organized by the Action members from Denmark that took place on 30 June to 01 July 2021.
Statistical models for infectious diseases epidemiology
16 September, 2021 
- 17 September, 2021
Venue: Piazzale Gambuli 1 - Edificio A - Piano 0 (Ellisse) 06132 Sant'Andrea delle Fratte Perugia, Italy
The Action members from Italy are organizing a two-day training school, hosted in Perugia, Italy [16 - 17 September 2021].
Bayesian Latent Class models for diagnostic test evaluation and true prevalence estimation
20 September, 2021 
- 22 September, 2021
Venue: Geopolis Campus, Larissa-Trikala ring-road, Larissa, 41500, Greece
The Action members from Greece are organizing a three-day training school, hosted in Larissa, Greece [20 - 22 September  2021]. Polychronis Kostoulas, Eleftherios Meletis, Konstantinos Pateras and Konstantinos Tsiamis are organizing a three-day training school. Topic "Bayesian Latent Class models for diagnostic test evaluation and true prevalence estimation".
Denmark Training School – Material
Main objective of HARMONY is to promote effective communication, training and understanding Bayesian Latent Class Models (BLCMs). You can access all training material, plus the recording, from the online training school on Diagnostic Test Evaluation organized by the Action members from Denmark that took place on 30 June to 01 July 2021.
Statistical models for infectious diseases epidemiology
16 September, 2021 
- 17 September, 2021
Venue: Piazzale Gambuli 1 - Edificio A - Piano 0 (Ellisse) 06132 Sant'Andrea delle Fratte Perugia, Italy
The Action members from Italy are organizing a two-day training school, hosted in Perugia, Italy [16 - 17 September 2021].
Diagnostic test evaluation with Bayesian Latent Class Models
23 September, 2021 
- 24 September, 2021
Venue: University College Dublin, Ireland
The Action members from Ireland are organizing a two-day training school, hosted by the University College Dublin, Ireland [23 - 24 September 2021].